Tuesday 20 March 2012

If you're interested in statins


Millions and millions of people have been taking statins for at least 3 decades yet we’re still only scratching the surface of our knowledge about their long-term risks and consequences.

3 interesting reports last week or so about exactly that.

First, the good news: one report linking statin use to a lower risk of developing Parkinson’s disease.

And a second report in the Canadian Medical Association Journal confirming previous studies that found a lower risk of pneumonia in statin users, a finding that could be of major importance to those at particularly high risk of pneumonia and its complications such as the immune-deficient, the seriously-ill hospitalized, and the elderly.

Finally, the one that really got my attention: a report in the New York Times by reporter Gretchen Reynolds on some work done by French researchers on rats that had been forced to run, some of whom were given statins, others not.

The rats given statins apparently “ran out of gas” much more quickly than the rats that hadn’t been given statins, and when the muscle tissue of the former was biopsied, the tissue showed persistent signs of injury.

Millions of people use statins and still try to exercise, as they all should, yet many also complain of muscle pain and fatigue when working out.

Could the drug be contributing to that fatigue?

For me, the benefits of statins to the high-risk person clearly outweigh the potential downsides of the drug.

But to the average-risk person for whom the benefits of the drug are minimal if present at all, say someone with a slightly high LDL level who is still eating properly and working out, if the drug is perhaps making them tired so that they don’t work out as much or don’t enjoy life as much, the drug may actually not be doing them any good.

Something to think about and discuss with your doctor, perhaps.