Thursday 19 July 2012

Good news or...


2 reports in the journal, Archives of Neurology, claim to have come up with accurate blood tests to detect which patients with mild cognitive impairment will go on to develop full-blown dementia.

The good news is that an accurate test that doesn’t result in too many false positive or false negatives would help very much in trials of drugs to treat dementia symptoms or prevent the progression of cognitive impairment, although the sad fact is that we have no such drugs currently and there are only a few in various stages of being studied.

In other words, we won’t have any better treatments for dementia for a long time so these blood tests will only be useful as a way of detecting dementia, and that’s not necessarily always a good thing.

In fact, in many situations, it might be a potentially negative thing (and very negative, at that).

That’s primarily because 1) we still can’t do much to alter the course of dementia, so presumably a few people who receive a positive test will become depressed, some perhaps depressed enough to commit suicide, and 2) there’s that factor of false positives that I mentioned earlier, which will obviously devastate the lives of the (few?) people who get that kind of result.