Thursday 12 July 2012

More menopause muddling


A coalition of 14 authoritative groups have just come together to publish a report on the use of hormone “replacement therapy” in which they – the groups – decry the apparent apprehension among both physician and patients to use as much of this HRT as these groups think should be used.

This is all because, they say, there has been way too much emphasis on that Women’s Health Initiative study from 2002 which found clearly overall higher risks than benefits to the use of HRT in the population that that study examined.

And that’s precisely the problem, these groups say, because (among several reasons that make this study less than exemplary), the women enrolled in the WHI study don’t really mimic the average women who would use HRT (the former were much older on average, and had long ago gone through menopause whereas most women who consider using HRT do so around the time they pass through menopause or shortly beyond it).

All of which, this report claims, means that so many women who could benefit from HRT aren’t getting any help, that is, women with moderate to severe symptoms of menopause for which there is really no effective therapy aside from hormones.

Bottom line, according to this report: women with such symptoms should consider the use of HRT, albeit for a “short” time.

The problem with that advice is simple: no one really knows yet what “short” means when it comes to raising the risk of HRT complications, especially the serious ones like breast cancer and blood clots.

Is it 6 months? A year? 2 years?

These groups say that the risk of blood clots is “very low” in women under the age of 60, so that shouldn’t really be a concern.

Yes, but if lots more women were using HRT, we’d definitely see a spike in blood clots in that age group, especially since it’s likely that the average weight of menopausal women is rising and obesity (along with a sedentary lifestyle) is a major risk factor for blood clots.

As well, another recent study found that the longer a woman takes HRT, the higher her risk of high blood pressure.

Does that risk kick in at 6 months? A year? 2 years? Does it cause damage even if the HRT is stopped after 6 months?

Who knows?

I’m not sure what I’d do if I were faced with the same problem but I do know this: for severe symptoms, nothing else works so if a woman decides to use HRT for symptoms that are overwhelming, she should use the lowest dose for the least amount of time that she can get away with, not settle for an arbitrary formula that says HRT should be taken for 2 years or 3 years, etc.